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Fetal heart remodeling

Elastin-producing valve interstitial cells stretch our understanding of cardiac valve remodeling

Nature Cardiovascular Research volume 3, pages 888–889 (2024)Cite this article

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The formation and remodeling of cardiac valves is a complex process that is crucial for normal development. A study now reveals a subpopulation of elastin-producing human valve interstitial cells that regulate fetal elastogenesis.

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Fig. 1: Schematic of aortic valve cell heterogeneity during maturation.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI, USA

    Joy Lincoln

  2. Herma Heart Institute, Children’s Wisconsin, Milwaukee, WI, USA

    Joy Lincoln

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  1. Joy Lincoln
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Correspondence to Joy Lincoln.

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The authors declare no competing interests.

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Lincoln, J. Elastin-producing valve interstitial cells stretch our understanding of cardiac valve remodeling. Nat Cardiovasc Res 3, 888–889 (2024). https://doi.org/10.1038/s44161-024-00509-w

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