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  • Matters Arising
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Risk of POTS after vaccine versus COVID-19 confounded

Matters Arising to this article was published on 11 September 2023

The Original Article was published on 12 December 2022

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Data availability

All data used in this Matters Arising are available in ref. 1.


  1. Kwan, A. C. et al. Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-CoV-2 infection. Nat. Cardiovasc. Res. 1, 1187–1194 (2022).

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Authors and Affiliations



The author (A.R.J.) made all contributions to the conception or design of the work; the acquisition, analysis and interpretation of data; drafted the work; approved the submitted version; and agreed both to be personally accountable for the author’s own contributions and to ensure that questions related to the accuracy or integrity of any part of the work are appropriately investigated, resolved and the resolution documented in the literature.

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Correspondence to Ari R. Joffe.

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The author declares no competing interests.

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Nature Cardiovascular Research thanks Jennifer Nicholas for her contribution to the peer review of this work.

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Joffe, A.R. Risk of POTS after vaccine versus COVID-19 confounded. Nat Cardiovasc Res 2, 871–872 (2023).

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