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In vivo monitoring of neutrophil trafficking to sites of injury

We report a new non-invasive approach to track neutrophils in both mice and humans by directing multimodal fluorine-loaded nanotracers equipped with specific binding peptides to neutrophil surface markers to enable background-free readout by in vivo 19F MRI.

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Fig. 1: Mapping the trafficking of mouse neutrophils after myocardial infarction.

References

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This is a summary of: Bouvain, P. et al. Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury. Nat. Cardiovas. https://doi.org/10.1038/s44161-022-00210-w (2023).

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In vivo monitoring of neutrophil trafficking to sites of injury. Nat Cardiovasc Res 2, 108–109 (2023). https://doi.org/10.1038/s44161-023-00216-y

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