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Will gazing into the single-cell multiome illuminate cardiovascular drug development?

Nature Cardiovascular Research volume 2, pages 97–99 (2023)Cite this article

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The rapid development of single-cell transcriptomics, epigenomics, proteomics and metabolomics has resulted in a wave of new biological discoveries. Here we explore what this has meant for the cardiovascular field and what the future might hold for developing treatments for patients.

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Fig. 1: Proposed future for cardiovascular drug discovery.

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Acknowledgements

T.X.Z. and Z.M. are supported by the British Heart Foundation, the NIHR Cambridge Biomedical Research Centre, Heart Research UK, and the UK Medical Research Council.

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Authors and Affiliations

  1. Department of Medicine, Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UK

    Tian X. Zhao & Ziad Mallat

  2. Department of Cardiology, Royal Papworth Hospital, Cambridge, UK

    Tian X. Zhao

  3. Université de Paris, PARCC, INSERM, Paris, France

    Ziad Mallat

Authors
  1. Tian X. Zhao
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  2. Ziad Mallat
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Correspondence to Tian X. Zhao or Ziad Mallat.

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Zhao, T.X., Mallat, Z. Will gazing into the single-cell multiome illuminate cardiovascular drug development?. Nat Cardiovasc Res 2, 97–99 (2023). https://doi.org/10.1038/s44161-022-00209-3

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