Sleep modulates cardiovascular health, and recent studies have begun to uncover underlying mechanistic links. An integrated translational approach that combines animal models and human trials will enrich scientific discovery, improve therapy, and help to alleviate the global burden of insufficient sleep and cardiovascular disease.
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This work was supported by National Institutes of Health (NIH) grants R00HL151750 and R01HL158534, and the Cure Alzheimer’s Fund (to C.S.M.).
The authors declare no competing interests.
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Cohen, O., Shah, N.A. & McAlpine, C.S. Sleep calibrates atherosclerotic cardiovascular disease. Nat Cardiovasc Res 1, 1104–1106 (2022). https://doi.org/10.1038/s44161-022-00190-x