Preemptive identification of unstable, ‘vulnerable’ atherosclerotic plaques is important for predicting the risk of thrombotic events. A new study shows that unbiased classification of human atherosclerotic plaques on the basis of transcriptomic features identifies subgroups with distinct biology and clinical presentation.
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Bashore, A.C., Zhu, L.Y. & Reilly, M.P. A new era in understanding atherosclerotic plaques. Nat Cardiovasc Res 1, 1127–1129 (2022). https://doi.org/10.1038/s44161-022-00187-6
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DOI: https://doi.org/10.1038/s44161-022-00187-6