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Categorizing atherosclerotic plaques by gene expression

Clustering the atherosclerotic plaques of patients based on gene expression unearths novel and clinically relevant heterogeneity beyond the established dogma of ‘stable’ and ‘unstable’ plaques.

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Fig. 1: Unsupervised clustering of plaques based on transcriptomics data.

References

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This is a summary of: Mokry, M. et al. Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-022-00171-0 (2022).

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Categorizing atherosclerotic plaques by gene expression. Nat Cardiovasc Res 1, 1134–1135 (2022). https://doi.org/10.1038/s44161-022-00174-x

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