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Myocardial infarction

Mapping the border zone in myocardial infarction

Nature Cardiovascular Research volume 1, pages 978–979 (2022)Cite this article

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The border zone in myocardial infarction is of key importance for the remodeling process that drives heart failure and sudden cardiac death. Two studies have now performed single-nucleus and spatial mapping of mouse myocardial infarction to provide novel insights into spatiotemporal events in the border zone.

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Fig. 1: Delineation of cardiac zones after MI.

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Authors and Affiliations

  1. Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany

    Sikander Hayat & Rafael Kramann

  2. Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany

    Rafael Kramann

  3. Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, the Netherlands

    Rafael Kramann

Authors
  1. Sikander Hayat
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  2. Rafael Kramann
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Corresponding author

Correspondence to Rafael Kramann.

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Competing interests

S.H. has funding from Novo Nordisk. R.K. has grants from Travere Therapeutics, Galapagos, Chugai and Novo Nordisk, and is a consultant or received honoraria from Bayer, Pfizer, Novo Nordisk, Lilly-Pharma and Gruenenthal.

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Hayat, S., Kramann, R. Mapping the border zone in myocardial infarction. Nat Cardiovasc Res 1, 978–979 (2022). https://doi.org/10.1038/s44161-022-00161-2

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