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Atherosclerosis

GPR55 is a key player for B-cell-mediated atheroprotection

Nature Cardiovascular Research volume 1, pages 982–983 (2022)Cite this article

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B cells have an essential role in regulating atherogenesis. A new study shows that the orphan receptor GPR55 is a pivotal modulator of B cell maturation and immunoglobulin production. This new finding identifies a previously uncharacterized protein involved in regulation of atherosclerosis by the immune system.

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Acknowledgements

A.R.R. is supported by la Caixa Banking Foundation under the project code HR17-00247 and by PID2019-106773RB-I00/AEI/10.13039/501100011033 grant from Ministerio de Ciencia e Innovación and co-funding by Fondo Europeo de Desarrollo Regional (FEDER). The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia e Innovación and the Pro CNIC Foundation and is a Severo Ochoa institute (CEX2020-001041-S grant funded by MCIN/AEI /10.13039/501100011033).

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  1. B Lymphocyte Biology Laboratory, Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain

    Almudena R. Ramiro

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  1. Almudena R. Ramiro
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Correspondence to Almudena R. Ramiro.

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Ramiro, A.R. GPR55 is a key player for B-cell-mediated atheroprotection. Nat Cardiovasc Res 1, 982–983 (2022). https://doi.org/10.1038/s44161-022-00159-w

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