LTBP-2 expression is increased in the right ventricle and plasma of patients with pulmonary arterial hypertension. Circulating levels of LTBP-2 correlate with right ventricular function and predict long-term survival in two independent cohorts of patients with pulmonary arterial hypertension.
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This is a summary of: Boucherat, O. et al. Identification of LTBP-2 as a plasma biomarker for right ventricular dysfunction in human pulmonary arterial hypertension. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-022-00113-w (2022).
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From heart to blood: LTBP-2 is a promising biomarker for pulmonary arterial hypertension. Nat Cardiovasc Res 1, 804–805 (2022). https://doi.org/10.1038/s44161-022-00121-w