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From heart to blood: LTBP-2 is a promising biomarker for pulmonary arterial hypertension

LTBP-2 expression is increased in the right ventricle and plasma of patients with pulmonary arterial hypertension. Circulating levels of LTBP-2 correlate with right ventricular function and predict long-term survival in two independent cohorts of patients with pulmonary arterial hypertension.

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Fig. 1: LTBP-2 expression in patients with PAH and correlation with prognosis.


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This is a summary of: Boucherat, O. et al. Identification of LTBP-2 as a plasma biomarker for right ventricular dysfunction in human pulmonary arterial hypertension. Nat. Cardiovasc. Res. (2022).

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From heart to blood: LTBP-2 is a promising biomarker for pulmonary arterial hypertension. Nat Cardiovasc Res 1, 804–805 (2022).

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