Collateral arteries may act as natural bypasses that reduce hypoperfusion after a coronary blockage. 3D imaging of neonatal and adult mouse hearts, plus human fetal and diseased adult hearts, is now used to computationally predict flow within the heart, and understand the cardioprotective role of collateral arteries in vivo.
This is a preview of subscription content, access via your institution
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 per month
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Timmis, A. et al. Eur. Heart J. 43, 716–799 (2022).
Virani, S. S. et al. Circulation 143, e254–e743 (2021).
Zhao, D. JACC Asia 1, 1–13 (2021).
Lazar, E. et al. Eur. Heart J. 38, 2333–2342 (2017).
Garbern, J. C. et al. Dev. Cell 57, 424–439 (2022).
Tian, X. et al. J. Mol. Cell. Cardiol. 167, 67–82 (2022).
Cortis, B. S. et al. Cardiologia 43, 77–81 (1998).
Wustmann, K. et al. Circulation 107, 2213–2220 (2003).
Seiler, C. Eur. J. Clin. Invest. 40, 465–476 (2010).
Zhang, H. et al. J. Mol. Cell. Cardiol. 87, 4–16 (2015).
He, L. et al. Cardiovasc. Res. 109, 419–430 (2016).
Das, S. et al. Cell 176, 1128–1142 (2019).
Anbazhakan, S. et al. Nat. Cardiovas. Res. https://doi.org/10.1038/s44161-022-00114-9 (2022).
Renier, N. et al. Cell 159, 896–910 (2014).
Kirst, C. et al. Cell 180, 780–795 (2020).
Olarte, O. E., Andilla, J., Gualda, E. J. & Loza-Alvarez, P. Adv. Opt. Photonics 10, 111–179 (2018).
D.M. is a founder and stakeholder of Swift Front.
Rights and permissions
About this article
Cite this article
Mayerich, D., Wythe, J.D. Computational insights on coronary artery function. Nat Cardiovasc Res 1, 691–693 (2022). https://doi.org/10.1038/s44161-022-00115-8