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A new tale of thalidomide repurposing

A prospective observational case-report study now shows that thalidomide can be a well-tolerated, efficacious treatment for complications such as pain, bleeding and ulceration from extracranial arteriovenous malformation.

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Fig. 1: Uncontrolled endothelial cell proliferation due to activation of multiple signaling pathways results in increased angiogenesis and AVM.


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Correspondence to Joyce M. C. Teng.

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The authors declare no competing interests.

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Teng, J.M.C., Siegel, D.H. A new tale of thalidomide repurposing. Nat Cardiovasc Res 1, 535–536 (2022).

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