Loss of transcription factor SMAD3 changes the smooth muscle cell (SMC) to a unique remodeling SMC phenotype and points to a potential role for SMAD3 in the inhibition of macrophage recruitment and outward remodeling of the aortic wall.
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Goumans, M.J., Quax, P.H.A. R-SMAD in control of the R-smooth muscle cell. Nat Cardiovasc Res 1, 289–290 (2022). https://doi.org/10.1038/s44161-022-00050-8
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DOI: https://doi.org/10.1038/s44161-022-00050-8
