Chemical selenylation of sulfur carrier proteins enables enzymatic incorporation of selenium into small molecules, thereby advancing a biocatalytic method for C–Se bond formation and chemoenzymatic selenometabolite synthesis.
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Kayrouz, C.M., Seyedsayamdost, M.R. Making selenometabolites nature’s way. Nat. Synth 3, 426–427 (2024). https://doi.org/10.1038/s44160-024-00483-y
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DOI: https://doi.org/10.1038/s44160-024-00483-y