A strategy for the cobalt-catalysed allylic fluoroalkylation of terpenes can provide site-selective access to various fluorine-containing motifs under mild conditions. The extension of the protocol to a 2-mol-scale synthesis indicates the scalability of this method.
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This is a summary of: Wang, S. et al. Cobalt-catalysed allylic fluoroalkylation of terpenes. Nat. Synth. https://doi.org/10.1038/s44160-023-00365-9 (2023).
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A strategy for the site-selective allylic fluoroalkylation of terpenes. Nat. Synth (2023). https://doi.org/10.1038/s44160-023-00369-5