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Stereocontrolled polymerization

Porphyrins pave the way to precision polymers

Stereocontrolled radical polymerizations are elusive, owing to the difficulty of controlling facial addition at a propagating planar, sp2 radical chain end. Now, cobalt–porphyrin initiators are reported that enable the preparation of well-defined, highly isotactic polyacrylamides at low Lewis acid loading.

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Fig. 1: Lewis-acid-tethered cobalt–porphyrin complexes enable preparation of isotactic polyacrylamides.


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Correspondence to Aaron J. Teator.

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Wekasinghe, K., Teator, A.J. Porphyrins pave the way to precision polymers. Nat. Synth 2, 811–812 (2023).

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