Reductive anti-1,2-dimetallation of alkynes proceeds through the use of sodium dispersion as a reducing agent and an organomagnesium or organoaluminum halide as a reduction-resistant electrophile. The reaction stereoselectively generates trans-1,2-dimagnesio- or 1,2-dialuminoalkenes, which show useful reactivity.
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This is a summary of: Takahashi, F., Kurogi, T. & Yorimitsu, H. Synthesis of trans-1,2-dimetalloalkenes through reductive anti-dimagnesiation and dialumination of alkynes. Nat. Synth. https://doi.org/10.1038/s44160-022-00189-z (2022).
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Reactive trans-dimetallated alkenes from alkynes. Nat. Synth 2, 90–91 (2023). https://doi.org/10.1038/s44160-022-00190-6