Ring-forming reactions are at the heart of organic synthesis. Now, phenylene rings are synthesized from two isopropyl moieties on a gold surface. Resolving the intermediates of this (3+3) cycloaromatization reaction with atomic force microscopy offers mechanistic insight into the dimerization process.
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Peña, D., Gross, L. 3 + 3 makes the ring. Nat. Synth 1, 260–261 (2022). https://doi.org/10.1038/s44160-022-00041-4
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DOI: https://doi.org/10.1038/s44160-022-00041-4
