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PHOTOREDOX CATALYSIS

Giving ketones the green light

The α-arylation of ketones is a powerful synthetic strategy for the construction of C–C bonds, but general metal-free methods are scarce. Now, a green-light-mediated photoredox protocol enables this transformation, giving access to a broad range of useful building blocks and value-added biorelevant products.

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Fig. 1: A broadly applicable green-light-driven method for the metal-free α-arylation of ketones.

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Correspondence to Luca Dell’Amico.

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Goti, G., Dell’Amico, L. Giving ketones the green light. Nat Synth 1, 101–102 (2022). https://doi.org/10.1038/s44160-022-00026-3

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