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PHOTOCATALYSIS

Three catalysts tango with olefins

Nature Synthesis volume 1, pages 13–15 (2022)Cite this article

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Predictably activating C–H and C–C bonds for the synthesis of new materials remains a challenge within the synthetic community. A ternary catalytic dance between radicals, metals and light may unlock this puzzle.

The ability to forge C–C and C–X bonds lies at the heart of synthetic organic chemistry. Chemists strive to unlock new transformations to make molecules ranging from pharmaceuticals to industrial catalysts and energy-storage materials. However, selective functionalization of the hydrocarbon backbone of readily available chemical feedstocks remains elusive due to the stability and similarity of C–H bonds.

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Fig. 1: Design of a broadly applicable reaction for direct allylic C(sp³)–H arylation.

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  1. Twitter: @thiagoreschutz; @gabepgomes

Authors and Affiliations

  1. Department of Chemical Engineering, Federal University of Santa Maria, Santa Maria, Brazil

    Thiago Reschützegger

  2. Department of Chemistry, Saint Vincent College, Latrobe, PA, USA

    Thomas Syphan

  3. Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA, USA

    Gabriel dos Passos Gomes

  4. Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA

    Gabriel dos Passos Gomes

Authors
  1. Thiago Reschützegger
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  2. Thomas Syphan
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  3. Gabriel dos Passos Gomes
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Correspondence to Gabriel dos Passos Gomes.

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The authors declare no competing interests.

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Reschützegger, T., Syphan, T. & dos Passos Gomes, G. Three catalysts tango with olefins. Nat Synth 1, 13–15 (2022). https://doi.org/10.1038/s44160-021-00018-9

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  • DOI: https://doi.org/10.1038/s44160-021-00018-9

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