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Homme fatal: how males cause demise


While C. elegans males are known to induce demise of hermaphrodites, the mechanism underlying this phenomenon is poorly understood. Through transcriptomic analyses, Booth et al. identify specific hermaphrodite gene sets that respond to male pheromones, sperm and seminal fluid and can mediate premature death of hermaphrodites.

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Fig. 1: Males cause hermaphrodite demise through multiple ways.


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Correspondence to Joy Alcedo.

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Sifoglu, D., Alcedo, J. Homme fatal: how males cause demise. Nat Aging 2, 773–774 (2022).

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