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Inhibition of BIN2 extends reproductive lifespan

The fact that women’s reproductive lifespans are finite affects many personal decisions and is accompanied by postmenopausal side effects. Expansion of the reproductive lifespan could therefore have many benefits. Findings from Zhang and colleagues indicate that manipulation of BIN2 extends the reproductive lifespan of female mice, and hold promise for therapeutic development.

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Fig. 1: Manipulation of BIN2 extends reproductive lifespan in mouse.


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Correspondence to Karen Schindler.

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Schindler, K. Inhibition of BIN2 extends reproductive lifespan. Nat Aging 1, 977–979 (2021).

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