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Inhibition of microRNA turns back the CLOCK of hair follicle aging

A new study shows that increased microRNA-31 expression is associated with hair follicle aging. Genetic deletion of the microRNA or pharmacological inhibition of its downstream effectors suppresses hair follicle stem cell aging in mice.

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Fig. 1: Inhibition of miR-31 and its regulation MAPK/ERK signaling improve skin aging.


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Correspondence to Rui Yi.

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Zhang, C., Yi, R. Inhibition of microRNA turns back the CLOCK of hair follicle aging. Nat Aging 1, 753–754 (2021).

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