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Youthfulness begins in youth

Chronological age fails to capture how the process of aging differs between individuals. Variability in rates of biological aging in youth is related to anatomical and functional differences already visible by midlife. This portends substantially different aging outcomes that have individual- and societal-level implications.

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Fig. 1: The effects of aging are highly variable between individuals and have their origins in early life.


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Correspondence to William J. Jagust.

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Competing interests

W.J.J. has served as a consultant to Genentech, Roche, Biogen and Bioclinica.

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Jagust, W.J. Youthfulness begins in youth. Nat Aging 1, 239–240 (2021).

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