Extended Data Fig. 2: Changes in Myrf expression do not influence APJ-mediated oligodendrocyte differentiation. | Nature Aging

Extended Data Fig. 2: Changes in Myrf expression do not influence APJ-mediated oligodendrocyte differentiation.

From: Age-dependent decline in remyelination capacity is mediated by apelin–APJ signaling

Extended Data Fig. 2

a, Relative Myrf mRNA expression in cultured oligodendrocytes transfected with Myrf siRNA and control siRNA (n = 3). Each data point represents biologically independent experiments. P < 0.001. b, Relative Sox10 mRNA expression in cultured oligodendrocytes transfected with Myrf siRNA and control siRNA (n = 3). Each data point represents biologically independent experiments. P = 0.11. c, Relative Myrf mRNA expression in cultured oligodendrocytes treated with ML233 for 3 days and in control oligodendrocytes (n = 5). Each data point represents biologically independent experiments. P = 0.31. Data are the mean ± s.e.m. and were assessed using and two-tailed Welch’s t-test.

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