The human gut microbiota is comprised of a vast assortment of trillions of microbial cells belonging to hundreds of different species, differing substantially between individual hosts. A new study has systematically investigated the relationship of host age to gut microbes in a geographically restricted and ethnically homogeneous human cohort, revealing key differences across ages and sexes.
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Schmidt, T. S. B. B., Raes, J. & Bork, P. Cell 172, 1198–1215 (2018).
Burberry, A. et al. Nature 582, 89–94 (2020).
Falony, G. et al. Science 352, 560–564 (2016).
Zhang, X., Zhong, H., Kristiansen, K., Li, J. & Ji, L. Nat. Aging https://doi.org/10.1038/s43587-020-00014-2 (2020).
Forslund, K. et al. Nature 528, 262–266 (2015).
Costea, P. I. et al. Nat. Microbiol. 3, 8–16 (2018).
McCoy, A. N. et al. PLoS ONE 8, e53653 (2013).
O’Keefe, S. J. D. Nat. Rev. Gastroenterol. Hepatol. 13, 691–706 (2016).
He, M. et al. Front. Microbiol. 10, 1359 (2019).
Yurkovetskiy, L. et al. Immunity 39, 400–412 (2013).
Kwa, M., Plottel, C. S., Blaser, M. J. & Adams, S. J. Natl Cancer Inst. 108, djw029 (2016).
de la Cuesta-Zuluaga, J. et al. mSystems 4, e00261–19 (2019).
Nagpal, R. et al. Nutr. Heal. Aging 4, 267–285 (2018).
Keshavarzian, A. et al. Mov. Disord. 30, 1351–1360 (2015).
Vujkovic-cvijin, I. et al. Nature 587, 448–454 (2020).
The authors declare no competing interests.
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Özkurt, E., Hildebrand, F. Lifelong sex-dependent trajectories of the human gut microbiota. Nat Aging 1, 22–23 (2021). https://doi.org/10.1038/s43587-020-00019-x
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