Our non-randomized single-center clinical trial demonstrates the safety, cost-saving and time-saving potential of artificial intelligence (AI) assistance in the detection of breast cancer metastases in sentinel lymph nodes. AI assistance shows important benefits for pathologists and the laboratory workflow, which are needed as cancer incidence and diagnostics continue to rise.
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References
Andersson, Y., Frisell, J., Sylvan, M., de Boniface, J. & Bergkvist, L. Breast cancer survival in relation to the metastatic tumor burden in axillary lymph nodes. J. Clin. Oncol. 28, 2868–2873 (2010). This study demonstrates a worse prognosis for patients with micrometastases than for patients who are node-negative.
Flach, R. N. et al. CONFIDENT-trial protocol: a pragmatic template for clinical implementation of artificial intelligence assistance in pathology. BMJ Open 13, e067437 (2023). This paper reports the CONFIDENT-trial protocol, providing a pragmatic template for clinical implementation of AI-assistance in pathology.
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This is a summary of: van Dooijeweert, C. et al. Clinical implementation of artificial-intelligence-assisted detection of breast cancer metastases in sentinel lymph nodes: the CONFIDENT-B single-center, non-randomized clinical trial. Nat. Cancer https://doi.org/10.1038/s43018-024-00788-z (2024).
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AI-assisted detection of lymph node metastases safely reduces costs and time. Nat Cancer 5, 1139–1140 (2024). https://doi.org/10.1038/s43018-024-00795-0
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DOI: https://doi.org/10.1038/s43018-024-00795-0
