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LUNG CANCER

Keap1ing an eye on Slc33A1

Nature Cancer volume 1, pages 575–576 (2020)Cite this article

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KEAP1 is a tumor suppressor encoded by a gene commonly mutated in lung cancer. A systematic search for Keap1-mutant cancer vulnerabilities now reveals that Slc33a1 is a context-specific essential gene that represents a promising new anti-cancer target.

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Fig. 1: Targeting KEAP1-mutant lung cancer.

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Authors and Affiliations

  1. Department of Urology, University of California, San Francisco, San Francisco, CA, USA

    Luke A. Gilbert

  2. Department of Cellular & Molecular Pharmacology, University of California, San Francisco, CA, USA

    Luke A. Gilbert

  3. Helen Diller Family Comprehensive Cancer Center, San Francisco, San Francisco, CA, USA

    Luke A. Gilbert

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  1. Luke A. Gilbert
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Correspondence to Luke A. Gilbert.

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Gilbert, L.A. Keap1ing an eye on Slc33A1. Nat Cancer 1, 575–576 (2020). https://doi.org/10.1038/s43018-020-0072-0

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