The genomic landscape of advanced cancer

Despite recent advances in cancer treatment, metastasis and therapy resistance remain among the major causes of cancer-related deaths worldwide. A recent pan-cancer study provides a comprehensive molecular profile of advanced and post-therapy tumors, integrating whole-genome and transcriptomic analysis with clinical outcomes.

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Fig. 1: The POG570 advanced and post-therapy pan-cancer cohort.


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E.R. is supported by funds from the Massachusetts General Hospital Cancer Center, The Breast Cancer Alliance, and the Broad Institute.

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Correspondence to Esther Rheinbay.

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Rheinbay, E. The genomic landscape of advanced cancer. Nat Cancer 1, 372–373 (2020).

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