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Envisioning the future of precision oncology trials

Precision oncology trials based on cancer biomarkers have the potential to improve outcomes by guiding the optimal choice of therapies for patients. For this to be truly achieved, computational methods such as virtual molecular tumor boards, dynamic precision medicine and digital twins are needed to support cohort selection and trial enrollment at scale.

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Fig. 1: Paradigm for computationally driven decision support in precision oncology.

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Correspondence to Subha Madhavan.

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J.R.B. reports personal fees (consulting fee) from Perthera.

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Madhavan, S., Beckman, R.A., McCoy, M.D. et al. Envisioning the future of precision oncology trials. Nat Cancer 2, 9–11 (2021). https://doi.org/10.1038/s43018-020-00163-8

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