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Tailoring immunotherapy with liquid biopsy

Nature Cancer volume 1, pages 857–859 (2020)Cite this article

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Immunotherapy has changed the treatment paradigm for patients with cancer, but patient selection, response assessment and treatment duration require further refinement. A recent study reports that the kinetics of circulating tumor DNA reflect response and resistance to immunotherapy treatment across multiple cancer types and could be used to tailor treatment.

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Fig. 1: The kinetics pf ctDNA track the response to pembrolizumab treatment in the INSPIRE clinical trial.

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Authors and Affiliations

  1. Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia

    Jeanne Tie

  2. Division of Personalized Oncology, the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia

    Jeanne Tie

  3. Department of Medical Oncology, Western Health, Melbourne, Australia

    Jeanne Tie

  4. The Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia

    Jeanne Tie

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  1. Jeanne Tie
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Correspondence to Jeanne Tie.

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The author declares no competing interests.

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Tie, J. Tailoring immunotherapy with liquid biopsy. Nat Cancer 1, 857–859 (2020). https://doi.org/10.1038/s43018-020-00113-4

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