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Biological intelligence

DishBrain plays Pong and promises more

An in vitro biological system of cultured brain cells has learned to play Pong. This feat opens up an avenue towards the convergence of biological and machine intelligence.

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Fig. 1: DishBrain uses human and mouse brain cells to learn to play a game of Pong through a microelectrode array as the interface.


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This work was partially supported by US National Institutes of Health grants R01CA237267, R01EB032716 and R01EB031885.

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Correspondence to Ge Wang.

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The authors declare no competing interests.

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Goldwag, J., Wang, G. DishBrain plays Pong and promises more. Nat Mach Intell 5, 568–569 (2023).

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