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Mitochondrial disease

Mitochondrial transplants to treat mitochondrial dysfunction

Nature Metabolism (2024)Cite this article

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A new approach to treating mitochondrial disorders is based on the transplantation of healthy mitochondria, and improves symptoms and survival in a mouse model of Leigh syndrome — a paediatric mitochondrial disease that is characterized by failure to thrive, lactic acidosis, and progressive degeneration.

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Fig. 1: Different strategies for mitochondrial transplant.

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  1. Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, USA

    Alessandro Bitto

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  1. Alessandro Bitto
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Correspondence to Alessandro Bitto.

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The author declares no competing interests.

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Bitto, A. Mitochondrial transplants to treat mitochondrial dysfunction. Nat Metab (2024). https://doi.org/10.1038/s42255-024-01124-6

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