Adults with overweight or obesity who have been exercising regularly for at least a few years have distinct structural and biological characteristics in their abdominal subcutaneous adipose tissue. These changes could underlie improved cardiometabolic health outcomes in this population, when compared with well-matched sedentary adults with overweight or obesity.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Crewe, C., An, Y. A. & Scherer, P. E. The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. J. Clin. Invest. 127, 74–82 (2017). A review that presents how adipose tissue abnormalities contribute to tissue dysfunction and impaired metabolic health.
Cypess, A. M. Reassessing human adipose tissue. New Engl. J. Med 386, 768–779 (2022). A review that comprehensively summarizes the implications of human adipose tissue in metabolic health.
Ahn, C. et al. Exercise training remodels subcutaneous adipose tissue in adults with obesity even without weight loss. J. Physiol. 600, 2127–2146 (2022). An article that examines the effects of three months of exercise training on subcutaneous adipose tissue morphology and the proteome in adults with obesity.
Mozaffarian, D., Hao, T., Rimm, E. B., Willett, W. C. & Hu, F. B. Changes in diet and lifestyle and long-term weight gain in women and men. New Engl. J. Med. 364, 2392–2404 (2011). An article that presents the global trajectory of weight changes in ageing adults.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Ahn, C. et al. Years of endurance exercise training remodel abdominal subcutaneous adipose tissue in adults with overweight or obesity. Nat. Metab. https://doi.org/10.1038/s42255-024-01103-x (2024).
Rights and permissions
About this article
Cite this article
Long-term exercise training has positive effects on adipose tissue in overweight or obesity. Nat Metab 6, 1657–1658 (2024). https://doi.org/10.1038/s42255-024-01102-y
Published:
Issue Date:
DOI: https://doi.org/10.1038/s42255-024-01102-y