This study shows that a 10% weight loss induced by calorie restriction and multimodal exercise training results in a much greater increase in whole-body insulin sensitivity than matched weight loss induced by calorie restriction alone. This result underscores the importance of adding regular exercise to a weight loss programme, as it improves metabolic health.
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This is a summary of: Beals, J. W. et al. Dietary weight loss-induced improvements in metabolic function are enhanced by exercise in people with obesity and prediabetes. Nat. Metab. https://doi.org/10.1038/s42255-023-00829-4 (2023).
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Exercise increases the metabolic benefits of weight loss. Nat Metab 5, 1084–1085 (2023). https://doi.org/10.1038/s42255-023-00842-7