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Gut microbiome

A high-protein diet prevents weight regain

Sustained weight loss and weight maintenance are key challenges for the treatment of obesity. Here, the authors show that a high-protein diet following weight loss can protect against weight regain, through a process dependent on the gut microbiome.

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Fig. 1: A high-protein diet protects from weight regain through changes in the gut microbiome.


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Correspondence to Amir Zarrinpar.

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Competing interests

A.Z. is a cofounder of, and equity holder in, Endure Biotherapeutics.

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Zarrinpar, A. A high-protein diet prevents weight regain. Nat Metab 4, 1616–1617 (2022).

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