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Introducing the Lipidomics Minimal Reporting Checklist

Nature Metabolism volume 4, pages 1086–1088 (2022)Cite this article

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The rapid increase in lipidomic data has triggered a community-based movement to develop guidelines and minimum requirements for generating, reporting and publishing lipidomic data. The creation of a dynamic checklist summarizing key details of lipidomic analyses using a common language has the potential to harmonize the field by improving both traceability and reproducibility.

Since the early 2000s, lipid analysis by mass spectrometry (MS) has undergone substantial growth. This growth has benefited many scientific fields, and now lipid measurements are increasingly common in a diverse array of scientific fields and journals.

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Fig. 1: Graphical overview of the Lipidomics Minimal Reporting Checklist concept.

References

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Acknowledgements

This is an effort by the International Lipidomics Society. We thank Stefan Lehneis for his help with the website.

Author information

Author notes

  1. These authors contributed equally: Jeffrey G. McDonald, Christer S. Ejsing, Dominik Kopczynski, Michal Holčapek.

Authors and Affiliations

  1. Center for Human Nutrition and Department of Molecular Genetics, UT Southwestern Medical Center, Dallas, TX, USA

    Jeffrey G. McDonald

  2. Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Odense, Denmark

    Christer S. Ejsing

  3. Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany

    Christer S. Ejsing

  4. Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria

    Dominik Kopczynski & Robert Ahrends

  5. Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic

    Michal Holčapek & Denise Wolrab

  6. Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

    Junken Aoki

  7. Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan

    Junken Aoki

  8. RIKEN, Center for Integrative Medical Sciences, Yokohama, Japan

    Makoto Arita

  9. National Institute of Genetics, Mishima, Japan

    Masanori Arita

  10. Department of Chemistry, North Carolina State University, Raleigh, NC, USA

    Erin S. Baker

  11. MetaboHUB-Metatoul, National Infrastructure of Metabolomics and Fluxomics, Inserm I2MC, Toulouse, France

    Justine Bertrand-Michel

  12. Center for Environmental and Human Toxicology, Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA

    John A. Bowden

  13. Heidelberg University Biochemistry Center (BZH), University of Heidelberg, Heidelberg, Germany

    Britta Brügger

  14. Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, New South Wales, Australia

    Shane R. Ellis

  15. Illawarra Heath and Medical Research Institute, Wollongong, New South Wales, Australia

    Shane R. Ellis & Todd W. Mitchell

  16. Center for Membrane Biochemistry and Lipid Research, Faculty of Medicine Carl Gustav Carus of TU Dresden, Dresden, Germany

    Maria Fedorova

  17. Swansea University Medical School, Swansea, UK

    William J. Griffiths

  18. Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Xianlin Han

  19. Department of Medicine - Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Xianlin Han

  20. Institute of Pharmaceutical Sciences, University of Graz, Graz, Austria

    Jürgen Hartler

  21. Field of Excellence BioHealth – University of Graz, Graz, Austria

    Jürgen Hartler

  22. Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

    Nils Hoffmann

  23. Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA

    Jeremy P. Koelmel

  24. Core Facility Mass Spectrometry and Lipidomics, ZMF, Medical University of Graz, Graz, Austria

    Harald C. Köfeler

  25. Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, UK

    Valerie B. O’Donnell

  26. Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan

    Daisuke Saigusa

  27. Research Center Borstel - Leibniz Lung Center, Borstel, Germany

    Dominik Schwudke

  28. German Center for Infection Research, Thematic Translational Unit Tuberculosis, Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany

    Dominik Schwudke

  29. German Center for Lung Research (DZL), Airway Research Center North (ARCN), Research Center Borstel, Leibniz Lung Center, Borstel, Germany

    Dominik Schwudke

  30. Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany

    Andrej Shevchenko

  31. Office of Public Health Science, Food Safety and Inspection Service, US Department of Agriculture, Athens, GA, USA

    Candice Z. Ulmer

  32. Singapore Lipidomics Incubator (SLING), Department of Biochemistry, YLL School of Medicine, National University of Singapore, Singapore, Singapore

    Markus R. Wenk

  33. Metabolomics and Proteomics Core, Helmholtz Zentrum München, Neuherberg, Germany

    Michael Witting

  34. MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, China

    Yu Xia

  35. Institute of Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany

    Gerhard Liebisch

  36. Lipidomics Consulting Ltd., Esbo, Finland

    Kim Ekroos

Authors
  1. Jeffrey G. McDonald
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  2. Christer S. Ejsing
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  3. Dominik Kopczynski
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  4. Michal Holčapek
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  5. Junken Aoki
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  6. Makoto Arita
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  7. Masanori Arita
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  8. Erin S. Baker
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  9. Justine Bertrand-Michel
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  10. John A. Bowden
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  11. Britta Brügger
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  12. Shane R. Ellis
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  13. Maria Fedorova
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  14. William J. Griffiths
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  15. Xianlin Han
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  16. Jürgen Hartler
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  17. Nils Hoffmann
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  18. Jeremy P. Koelmel
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  19. Harald C. Köfeler
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  20. Todd W. Mitchell
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  21. Valerie B. O’Donnell
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  22. Daisuke Saigusa
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  23. Dominik Schwudke
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  24. Andrej Shevchenko
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  25. Candice Z. Ulmer
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  26. Markus R. Wenk
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  27. Michael Witting
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  28. Denise Wolrab
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  29. Yu Xia
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  30. Robert Ahrends
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  31. Gerhard Liebisch
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  32. Kim Ekroos
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Contributions

J.G.M., C.S.E., D.K. and M.K. contributed equally, wrote the manuscript and developed the online checklist. D.K. programmed the online checklist system. J.A., Makoto A., Masanori A., E.S.B., J.BM., J.A.B., B.B., S.R.E., M.F., W.J.G., X.H., J.H., N.H., J.P.K., H.C.K., T.W.M., V.B.O., D. Saigusa, D. Schwudke, A.S., C.Z.U., M.R.W., M.W., D.W. and Y.X. discussed and contributed to the manuscript. R.A., G.L. and K.E. jointly coordinated this work, wrote the manuscript and developed the online checklist. All authors annotated data and approved of the final manuscript.

Corresponding authors

Correspondence to Robert Ahrends, Gerhard Liebisch or Kim Ekroos.

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Competing interests

Kim Ekroos is the owner of Lipidomics Consulting Ltd.

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McDonald, J.G., Ejsing, C.S., Kopczynski, D. et al. Introducing the Lipidomics Minimal Reporting Checklist. Nat Metab 4, 1086–1088 (2022). https://doi.org/10.1038/s42255-022-00628-3

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