The fasting-mimicking diet is a five-day cycle of near total fasting each month that extends healthspan in male mice. In this issue of Nature Metabolism, Mishra et al. demonstrate life-extending and cardioprotective benefits of the fasting-mimicking diet in middle-aged female mice that are consuming a high-fat diet.
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References
Mitchell, S. J. et al. Cell Metab. 29, 221–228.e3 (2019).
Liu, K., Liu, B. & Heilbronn, L. K. Physiol. Behav. 218, 112827 (2020).
Brandhorst, S. et al. Cell Metab. 22, 86–99 (2015).
Mishra et al. Nat. Metab. https://doi.org/10.1038/s42255-021-00469-6 (2021)
Liu, B., Page, A. J., Hutchison, A. T., Wittert, G. A. & Heilbronn, L. K. Nutrition 66, 38–43 (2019).
Hutchison, A. T. et al. Obesity (Silver Spring) 27, 50–58 (2019).
Huang, J. et al. JAMA Intern. Med. 180, 1173–1184 (2020).
Wu, Y. et al. Cell Metab. 33, 888–904.e6 (2021).
Yu, D. et al. Cell Metab. 33, 905–922.e6 (2021).
Lam, Y. Y., Ghosh, S., Civitarese, A. E. & Ravussin, E. J. Gerontol. A Biol. Sci. Med. Sci. 71, 1258–1265 (2016).
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Heilbronn, L.K. Periodic fasting prevents fat penalties in females. Nat Metab 3, 1282–1283 (2021). https://doi.org/10.1038/s42255-021-00472-x
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DOI: https://doi.org/10.1038/s42255-021-00472-x