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ADIPOSE TISSUE

The genesis of brown fat—a smooth muscle origin story revisited

Nature Metabolism volume 3, pages 449–450 (2021)Cite this article

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Brown adipose tissue acquires increased thermogenic capacity with prolonged cold exposure through de novo recruitment of brown adipocytes. Studies by Shamsi et al. and Angueira et al. identify novel cellular origins of cold-induced brown adipocytes and further elucidate the molecular mechanism regulating the expansion of brown adipose tissue.

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Fig. 1: The cellular mechanism of brown adipogenesis.

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Authors and Affiliations

  1. Albert Einstein College of Medicine, Bronx, NY, USA

    Alana Deutsch

  2. Department of Medicine, Division of Endocrinology and Diabetes, Albert Einstein College of Medicine, Bronx, NY, USA

    Kosaku Shinoda

  3. Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA

    Kosaku Shinoda

  4. Fleischer Institute of Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA

    Kosaku Shinoda

Authors
  1. Alana Deutsch
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  2. Kosaku Shinoda
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Correspondence to Kosaku Shinoda.

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The authors declare no competing interests.

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Deutsch, A., Shinoda, K. The genesis of brown fat—a smooth muscle origin story revisited. Nat Metab 3, 449–450 (2021). https://doi.org/10.1038/s42255-021-00376-w

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