Genetic-interaction mapping and co-essentiality analyses in human cells reveal the orphan gene C12orf49 (also known as SPRING1) as a novel regulator of lipid-metabolism homeostasis.
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The authors declare no competing interests.
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Girardi, E., Superti-Furga, G. Caught in the genetic network: a novel regulator of lipid metabolism. Nat Metab 2, 483–484 (2020). https://doi.org/10.1038/s42255-020-0218-5