Di Gioia and colleagues report on how the oxidized phospholipid oxPAPC alters metabolism in macrophages via glutamine and oxaloacetate, thus boosting production of the cytokine IL-1β and promoting atherosclerosis.
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O’Neill, L.A.J. Targeting macrophage immunometabolism to prevent atherosclerosis. Nat Metab 1, 1173–1174 (2019). https://doi.org/10.1038/s42255-019-0154-4
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DOI: https://doi.org/10.1038/s42255-019-0154-4