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Gut feelings: microRNAs tune protein quality control and ageing to odours

A Publisher Correction to this article was published on 06 March 2019

This article has been updated

A new study in C. elegans identifies a microRNA-dependent mechanism that enables olfactory neurons to rapidly regulate protein degradation in the intestine and therefore organismal ageing.

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Fig. 1: Food odour triggers the miRNA mir-71 in olfactory neurons to regulate gut protein homeostasis and ageing.

Change history

  • 06 March 2019

    In the version of the article originally published, the study by Finger et al. was incorrectly described in one sentence in the third paragraph as implicating the microRNA mir-73 in the regulation of proteostasis; mir-71 was the correct microRNA. The error has been corrected in the HTML and PDF versions of the article.


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Correspondence to Coleen T. Murphy.

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Kaletsky, R., Murphy, C.T. Gut feelings: microRNAs tune protein quality control and ageing to odours. Nat Metab 1, 306–307 (2019).

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