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A question of identity: Tbx3 carries the POMC flag

Nature Metabolismvolume 1pages175176 (2019) | Download Citation

Hypothalamic neuronal diversity is at the core of whole-body energy-homeostasis control, but the molecular mechanisms governing neuronal neuropeptide specification remain incompletely understood. A new study in Nature Metabolism adds a relevant piece to the puzzle of how key hypothalamic neuronal populations maintain their peptidergic identity throughout the lifespan.

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Acknowledgements

A.O. is supported by the Beatriu de Pinós programme from the Generalitat de Catalunya. M.C. is supported as a recipient of a Miguel Servet 2 contract (MSII15/00025) from Instituto de Salud Carlos III and is cofinanced by Fondo Europeo de Desarrollo Regional (FEDER), Unión Europea, ‘Una manera de hacer Europa’.

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Affiliations

  1. Neuronal Control of Metabolism Laboratory, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

    • Arnaud Obri
    •  & Marc Claret
  2. Centro de Investigación Biomédica en Red (CIBER) de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain

    • Marc Claret

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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Marc Claret.

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DOI

https://doi.org/10.1038/s42255-018-0027-2

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