Hypothalamic neuronal diversity is at the core of whole-body energy-homeostasis control, but the molecular mechanisms governing neuronal neuropeptide specification remain incompletely understood. A new study in Nature Metabolism adds a relevant piece to the puzzle of how key hypothalamic neuronal populations maintain their peptidergic identity throughout the lifespan.
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Acknowledgements
A.O. is supported by the Beatriu de Pinós programme from the Generalitat de Catalunya. M.C. is supported as a recipient of a Miguel Servet 2 contract (MSII15/00025) from Instituto de Salud Carlos III and is cofinanced by Fondo Europeo de Desarrollo Regional (FEDER), Unión Europea, ‘Una manera de hacer Europa’.
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Affiliations
Neuronal Control of Metabolism Laboratory, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
- Arnaud Obri
- & Marc Claret
Centro de Investigación Biomédica en Red (CIBER) de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain
- Marc Claret
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The authors declare no competing interests.
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Correspondence to Marc Claret.
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