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VASCULAR DISEASE

Lnc-ing microRNA activity to atheroprotection

Cholesterol accumulation in cells and blood vessels promotes the development of vascular diseases. The long non-coding RNA CHROME can help clear excess cholesterol and provide protection from atherosclerosis.

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Fig. 1: Model for CHROME actions in atherosclerosis.

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Correspondence to Peter Tontonoz.

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Sallam, T., Tontonoz, P. Lnc-ing microRNA activity to atheroprotection. Nat Metab 1, 10–11 (2019). https://doi.org/10.1038/s42255-018-0012-9

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