Medical isotope production with the IsoDAR cyclotron

Jose R. Alonso and colleagues describe technical advances that will allow the proposed IsoDAR (isotope decay at rest) cyclotron — being developed for neutrino physics research — to produce many medical isotopes more efficiently than existing cyclotrons can.

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References

  1. 1.

    Schmor, P. Review of cyclotrons for the production of radioactive isotopes for medical and industrial applications. Rev. Accel. Sci. Technol. 4, 103–116 (2011).

    Article  Google Scholar 

  2. 2.

    Bungau, A. et al. Proposal for an electron antineutrino disappearance search using high-rate 8Li production and decay. Phys. Rev. Lett. 109, 141802 (2012).

    ADS  Article  Google Scholar 

  3. 3.

    Alonso, J. R. et al. Isotope production from the IsoDAR cyclotron. Preprint at arXiv https://arxiv.org/abs/1807.06627 (2018).

  4. 4.

    Calabretta, L., Rifuggiato, D. & Shchepounov, V. High intensity proton beams from cyclotrons for H2 +. IEEE https://accelconf.web.cern.ch/accelconf/p99/PAPERS/THP139.PDF (1999).

  5. 5.

    Conrad, J. MRI: development of the IsoDAR front-end. National Science Foundation https://www.nsf.gov/awardsearch/showAward?AWD_ID=1626069 (2017).

  6. 6.

    Miederer, M., Scheinberg, D. & DcDevitt, M. Realizing the potential of the actinium-225 radionuclide generator in targeted alpha-particle therapy applications. Adv. Drug Deliv. Rev. 60, 1371–1382 (2008).

    Article  Google Scholar 

  7. 7.

    Weidner, J. W. et al. Proton induced cross sections relevant to production of 225Ac and 223Ra in natural thorium targets below 200 MeV. Appl. Radiat. Isot. 70, 2602–2607 (2011).

    Article  Google Scholar 

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Correspondence to Jose R. Alonso.

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Alonso, J.R., Barlow, R., Conrad, J.M. et al. Medical isotope production with the IsoDAR cyclotron. Nat Rev Phys 1, 533–535 (2019). https://doi.org/10.1038/s42254-019-0095-6

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