Understanding food properties is paramount for enhancing features such as appearance, taste and texture, for improving health-related factors such as minimizing the onset of allergies or improving the digestibility of nutrients, and for preserving food and extending its shelf-life. This Review discusses the challenges and opportunities offered by analysing foods as soft condensed matter systems. Emphasis is placed on the three main macronutrients constituting the main building blocks of foods: polysaccharides, proteins and lipids. Similarities and differences with synthetic polymers, colloids and surfactants are described. This Review also discusses the lessons that can be learned from soft matter approaches and the extent of their applicability to real foods.
The theoretical tools developed in soft condensed matter physics provide a means to describe foods and macronutrients at scales ranging from angstroms to tens of micrometres.
Polymer physics can be used to characterize the properties of polysaccharides and unfolded proteins, whose complex nature poses unusual theoretical questions.
Dispersions and gels based on proteins can be described by the physics of colloids and aggregates, and their phase diagrams can be rationalized accordingly.
The structural properties of food emulsions and targeted delivery of macronutrients from lipid-based mesostructures can be studied and controlled with the aid of surfactant physics and transport theory.
Some experimental soft matter tools are currently underexploited in food science, which calls for further theoretical research in soft condensed matter physics.
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The authors are indebted to W. K. Fong and M. Usuelli for discussions and thank A. Diego-González for producing the mayonnaise sample reported in Fig. 1a.
The authors declare no competing interests.
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Nature Reviews Physics thanks E. Zaccarelli, N. Brooks and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.
Loss of secondary, tertiary and/or quaternary structure of a protein owing to temperature or chemical stress, for example.
- Amyloid fibrils
Protein and peptide-based fibrous aggregates with a characteristic cross-ß secondary structure.
- Thermal blob
The portion of chain length whose total interaction energy is of the order of kBT.
When peptide chains are fragmented into shorter subunits by chemical, enzymatic or thermal stimuli.
- Hamaker constant
A quantity with the units of energy characterizing the van der Waals interactions between colloids.
- Second virial coefficient
A quantity with units of volume describing the net two-body interactions between two particles; positive and negative values indicate net repulsion and attraction, respectively.
- Association kinetics
Dynamic features of binding between particles, usually characterized by suitable rate constants.
- Isoelectric point
Value of pH for which partial protonation induces a net zero charge in a molecule hosting several positively charged and negatively charged groups.
- Storage modulus
Parameter with the units of pressure quantifying the elastic response of a viscoelastic material to an external stress.
- Block copolymers
Macromolecules obtained by covalently joining two polymers with different physico-chemical properties by one end.
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Assenza, S., Mezzenga, R. Soft condensed matter physics of foods and macronutrients. Nat Rev Phys 1, 551–566 (2019). https://doi.org/10.1038/s42254-019-0077-8