a Representative images and quantification of microvascular sprouting area from Naxe−/− and WT adult mouse choroid explants. N = 3 choroid explants for WT, 4 for Naxe−/− mice. b Representative images of CNV lesions labeled by Alexa 568-isolectin on RPE-choroid flatmounts and quantification of CNV areas from Naxe−/− and WT adult mice. N = 33 laser spots per group. c Representative images of CNV lesions and quantification of CNV areas after intravitreal injection of a rabbit anti-AIBP antibody or a control IgG. N = 28 laser spots per group. Scale bar is 20 µm in b and c. Data represent mean ± SEM in a–c. Statistical analysis was performed by two-tailed Student’s t-test.