Fig. 2: Sequence-specific catch-and-release of ssDNA-tagged molecules. | Communications Biology

Fig. 2: Sequence-specific catch-and-release of ssDNA-tagged molecules.

From: A smart polymer for sequence-selective binding, pulldown, and release of DNA targets

Fig. 2

a Schematic stepwise separation of two fluorescent dyes. T1: Cy5; T2: Cy3. Black anchors symbolize the methanol-responsive polymer backbone. b Photographs of tubes containing MeRPy-10 and a mixture of the dyes. MeRPy-10 was programmed to capture either T1 (upper path) or T2 (lower path). The target was then pulled down and isolated by the addition of methanol and a short spin-down. After separation, targets were released by TMSD.

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