Fig. 7: Compound treatment of individual T-cell or spheroid cellular populations reveals the compound mechanism of action. | Communications Biology

Fig. 7: Compound treatment of individual T-cell or spheroid cellular populations reveals the compound mechanism of action.

From: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function

Fig. 7

a T-cells were treated with hit compounds or DMSO vehicle control for 48 h and phenotypically profiled by FACS. b Tumor spheroid cultures were treated with hit compounds or DMSO vehicle control for 48 h and phenotypically profiled by FACS. An independent sample t-test was used to calculate probability where *p < 0.05, **p < 0.01, ***p < 0.001; n = 3 independent experiments and error bars indicate standard deviation.

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