Fig. 2 | Communications Biology

Fig. 2

From: Forecasting cell fate during antibiotic exposure using stochastic gene expression

Fig. 2

Bacterial promoters have different predictive power in the presence of carbenicillin. a Variable death times of cells depending on initial fluorescence. As in Fig. 1c, the x-axis shows cumulative percentage of dead cells over time and y-axis represents binned deciles according to initial fluorescence at t = 0. For the bins and initial fluorescence distributions for each reporter see Supplementary Fig. 2. At least five replicate microscopy positions with ~100 cells each were pooled before binning. b Peak mutual information between the initial fluorescence and cell fate for each reporter strain. c Information over time for each strain. For visual clarity, the data are divided onto two plots, one of which shows the four reporters with the highest peak information and the other showing the remaining reporter data. d Differences in time to reach 50% cell death between the fluorescence decile with the fastest dying cells and the decile with the slowest dying cells. Savitzky–Golay filter was used to smooth data across deciles before calculating the minimum and maximum values

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